Researching ESM_IPN: Boron on GPCR

PhD., M.D. Marvin Antonio Soriano Ursúa.

MEDICAL DEGREE:
2000-2007 SCHOOL OF MEDICINE (1st june 2007). ESCUELA SUPERIOR DE MEDICINA, INSTITUTO POLITECNICO NACIONAL (IPN). LICENCIATURA MEDICO CIRUJANO Y PARTERO.
GRADUATE TRAINING:
2005.2006 INTERNSHIP AT INNCMyN ‘SALVADOR ZUBIRAN’.
2006-2007 SOCIAL SERVICE IN RESEARCH.
2007-2009 MASTER SCIENCE DEGREE (PHARMACOLOGY, MPharm).
2009- 2012 PhD (Research in Medicine).

AWARDS:
03-MAR-2004 AWARD OF ARMY SCHOOL OF MEDICINE (MEXICO) FOR 3RD PLACE AT THE STUDENT POSTER COMPETITION (IV CONGRESS OF MEDICAL STUDENTS).
08-NOV-2005 AWARD BY ACADEMIC DEPARTMENT OF IPN BY EXCELENT PERMORMANCE DURING THE SCHOLAR CYCLES 2003-2004 AND 2004-2005.
03-MAR-2007 HONORIFIC MENTION AT STUDENT POSTER COMPETITION. BANFF, ALBERTA CANADA, WPS-2007.
01-JUN-2007 HONORIFIC MENTION AT MEDICAL DEGREE.
10-NOV-2007 AWARD TO 2ND PLACE. ‘THE BEST THESIS COMPETITION IN MEDICAL-BIOLOGICAL AREA OF IPN’.
12-FEB-2009 1ST PLACE AT STUDENT POSTER COMPETITION. ACAPULCO, GUERRERO, MEXICO, WPS-2009.
19-JUN-2009 HONORIFIC MENTION AT MASTER DEGREE.
06-NOV-2009 THE BEST POSGRADUATE THESIS AWARD, IPN,MEXICO.
18-MAY-2011 PRESEA LAZARO CARDENAS, THE GREATEST AWARD BY IPN.
20-NOV-2012 Award as Thesis Director of the best Thesis in Biology Sciences at IPN.
20-NOV-2013 National award for Young in Science and Technology.
18-DEC-2013 THE BEST POSGRADUATE -PhD- THESIS AWARD, IPN,MEXICO.

TEACHING ACTIVITIES:
01-AUG-07-AT PRESENT Professor, DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA, ESCUELA SUPERIOR DE MEDICINA, IPN.

Articles:

2009
1. Synthesis, pharmacological and in silico evaluation of 1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo[4.4.0]deca-7,9,11-trien-9-yl)-2-(tert-butylamino)ethanol, a compound designed to act as a beta2 adrenoceptor agonist. Soriano-Ursúa MA, Valencia-Hernández I, Arellano-Mendoza MG, Correa-Basurto J, Trujillo-Ferrara JG. Eur J Med Chem. 2009;44(7):2840-6.
2. Homology modeling and flex-ligand docking studies on the guinea pig beta(2) adrenoceptor: structural and experimental similarities/ differences with the human beta(2). Soriano-Ursúa MA, Trujillo-Ferrara JG, Correa-Basurto J.J Mol Model. 2009;15(10):1203-11.
2010
3. Docking studies on a refined human beta(2) adrenoceptor model yield theoretical affinity values in function with experimental values for R-ligands, but not for S-antagonists. Soriano-Ursúa MA, Trujillo-Ferrara JG, Alvarez-Cedillo J, Correa-Basurto J. J Mol Model. 2010;16(3):401-9.
4. Pharmacokinetic parameters and a theoretical study about metabolism of BR-AEA (a salbutamol derivative) in rabbit. Soriano-Ursúa MA, Correa-Basurto J, Romero-Huerta J, Elizalde-Solis O, Galicia-Luna LA, Trujillo-Ferrara JG. J Enzyme Inhib Med Chem. 2010; 25(3):340-346.
5. Scope and Difficulty in Generating Theoretical Insights Regarding Ligand Recognition and Activation of the beta(2) Adrenergic Receptor. Soriano-Ursúa MA, Trujillo-Ferrara JG, Correa-Basurto J. J Med Chem. 2010;53(3):923-32.
6. Design, synthesis and in vitro evaluation of (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenyl hydrogen phenylboronate: A novel salbutamol derivative with high intrinsic efficacy on the beta(2) adrenoceptor. Soriano-Ursúa MA, Correa-Basurto J, Valencia-Hernández I, Amezcua-Gutiérrez MA, Padilla-Martínez II, Trujillo-Ferrara JG. Bioorg Med Chem Lett. 2010;20: 5623-5629.
2011
7. Homology model and docking studies on porcine β(2) adrenoceptor: description of two binding sites. Soriano-Ursúa MA, Correa-Basurto J, Trujillo-Ferrara JG, Kaumann AJ.J Mol Model. 2011; 17(10):2525-38.
8. Theoretical study about high 3-D molecular similarity and ligand binding modes of orthologous human/rat D2 dopamine receptor. Marvin A. Soriano-Ursúa, Jorge O. Ocampo-López, Karina Ocampo-Mendoza, José G. Trujillo-Ferrara, José Correa-Basurto. Comput Biol Med. 2011; 41(7):537-45.
9. Genotype-phenotype discordance in Duchenne Muscular Dystrophy patient due to a novel mutation. López-Hernández LB, Van Heusden D, Soriano-Ursúa MA, Figuera-Villanueva L, Vázquez-Cárdenas NA, Sandoval-Ramírez L, Canto P, Gómez-Díaz B and Coral-Vázquez RM. Rev Neurol. 2011; 52(12):720-4.
10. Give boron a chance: Boron containing compounds reach ionotropic and metabotropic transmembrane receptors. Soriano-Ursúa MA, Mancilla-Percino T, Correa-Basurto J, Querejeta E and Trujillo-Ferrara JG. Mini Rev Med Chem. 2011; 11(12):1031-8.
2012
11. Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the human beta2-adrenoceptor. Soriano-Ursúa MA, McNaught-Flores DA, Nieto-Alamilla G, Segura-Cabrera A, Correa-Basurto J, Arias-Montaño JA, Trujillo-Ferrara JG. Bioorg Med Chem. 2012; 20:933–941.
12. Clinical Implications of Recent Insights into the Structural Biology of Beta2 Adrenoceptors. Amezcua-Gutiérrez MA, Ciprés-Flores FJ, Trujillo-Ferrara JG, Soriano-Ursúa MA. Curr Drug Targets 2012; 13(1):1336-46.
2013
13. -Alkylselenenylated benzoic acid accesses several sites in serum albumin according to fluorescence studies, Raman spectroscopy and theoretical simulations. Federico Martinez-Ramos, Yadira Fonseca-Sabater, Marvin A. Soriano-Ursúa, Eduardo Torres, Martha C. Rosales-Hernández MC, José G. Trujillo-Ferrara, Luis E. Tolentino-Lopez, Ilizaliturri-Flores Ian and José Correa-Basurto. Protein Pept Lett. 2013; 20(6):705-14.14. Notable advances in medicine from the structural biology of catecholamine-receptors. Marvin A. Soriano-Ursúa*, Eunice D. Farfán-García, José G. Trujillo-Ferrara. Acta Medica Politecnica. Spanish. 2013; 1(2):17-22.15. In Vitro And Molecular Modeling Analysis Of Two Mutant Desert Hedgehog (Dhh) Proteins Associated With 46,XY Gonadal Dysgenesis. Castro JJ, MéndezJP, Coral-VázquezRM, Soriano-Ursúa MA, Damian-MatsumuraP, Benítez JG, Rosas-Vargas H and Canto P. DNA and Cell Biology. 2013; 32(9):524-30.16. Insights into the structural biology of GPCRs impacts drug design for CNS neurodegenerative processes. (FREE ACCESS) Farfán-García  Eunice D., Trujillo-Ferrara José G., Castillo-Hernández María C., Guerra-Araiza Christian H., Soriano-Ursúa Marvin A*. Neural Regeneration Research, 2013; 8(24):2290-302.17. Homology modeling, molecular dynamics and docking simulations of rat A2A receptor, a three-dimensional model validate under QSAR studies. Luis C. Jimenez-Botello, Marvin A. Soriano-Ursúa, Omar Deeb, Aldo Segura-Cabrera, M Martínez-Archundia and J Correa-Basurto. Current Trends in Medicinal Chemistry. 2013; 7:35-52. (ISSN: 0973-0532).18. Recent Structural advances of beta1 and beta2 adrenoceptors yield keys for ligand recognition and drug design. J Med Chem. 2013; 56:8207-8223. DOI: 10.1021/jm400471z.19. Histamine modulates isoproterenol efficacy at the b₂adrenoceptor: Inferences regarding allosteric modulation byimidazole-containing compounds (OPEN ACCESS). Marvin A. Soriano-Ursúa^*, Daniel McNaught-Flores,José Correa-Basurto, José A. Arias-Montaño, José G. Trujillo-Ferrara. Biochemistry & Physiology. ISSN:2168-9652. 2013; 2: 114. doi: 10.4172/2168-9652.1000114.
2014
20. Molecular dynamics simulations to explore the active/inactive conformers of guinea pig β2 adrenoceptor for selective agonists or antagonists design. A. Segura-Cabrera, C. A. García-Pérez, F.J. Ciprés-Flores, R. I. Cuevas-Hernández, J. G. Trujillo-Ferrara, J. Correa-Basurto, M. A. Soriano-Ursúa*. Molecular Simulation. 2014;40(15):1244-1254.  http://dx.doi.org/10.1080/08927022.2013.857771.
21. Boron-containing acids: Preliminary evaluation of acute toxicity and access to the brain determined by Raman scattering spectroscopy. Marvin A. Soriano-Ursúa^*, Eunice D. Farfán-García, Yessica López-Cabrera, E. Querejeta, José G. Trujillo-Ferrara. NeuroToxicology. 2014; 40:8-15.
22. Boron containing compounds: Chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy. Marvin A. Soriano-Ursúa*, Bashkar C. Das, José G. Trujillo-Ferrara. Expert Opinion on Therapeutics Patents.2014_;4(5):485-500. DOI:10.1517/13543776.2014.881472. Recomendado por el editor (http://informahealthcare.com/doi/story/10.1517/news.2014.05.15.784)
23. Anticonvulsant effects of bis-1,4-dihydropyridines and the probable role of l-type calcium channels suggested by docking simulations. Ramírez-San Juan E, Soriano-Ursúa MA, Espinosa-Raya J, Correa-Basurto J, Trujillo-Ferrara J, Miranda-Ruvalcaba R, Delgado-Reyes F, Gómez-Pliego R. Med Chem Res. (ISSN:1054-2523) 2014; 23:5149-5159.
24. Enfermedad de Alzheimer: Topicos actuales sobre su etiopatogenia y propuestas sobre la terapeutica farmacológica. Ciprés-Flores FJ, Soberanes-Gutiérrez E, Domínguez-Campos A, Trujillo-Ferrara JG,  Soriano-Ursúa MA^*. Acta Medica Politecnica. 2014.
2015
25. Triallelic digenic mutation in the prokineticin 2 and GNRH receptor genes in two brothers with –normosmic congenital hypogonadotropic hypogonadism. Mendez JP, Zenteno JC, Coronel A, Soriano-Ursúa MA, Valencia-Villalvazo EY, Soderlund D, Coral-Vazquez RM, Canto P. Endocrine Res. (ISSN: 0743-5800) 2015; 40 (3):166-171.
26. Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting the beta2 adrenoceptor. Marvin A. Soriano-Ursúa*, José A. Arias-Montaño, José Correa-Basurto, Christian F. Hernández-Martínez, Yessica López-Cabrera, Maria C. Castillo-Hernández, Itzia I. Padilla-Martínez, José G. Trujillo-Ferrara. Bioorg Med Chem Lett (ISSN: 0960-894X). 2015; 25(4):820-5.
27. Insights into a defined secondary binding region on β-adrenoceptors and putative roles in ligand binding and drug design. Marvin A. Soriano-Ursúa, José G. Trujillo-Ferrara, José A. Arias-Montaño, Rafael Villalobos-Molina. MedChemComm. 2015; 6, 991-1002. ISSN:2040-2503.
28.  Hepatoprotective effect of Geranium schiedeanum against ethanol toxicity during liver regeneration. Madrigal-Santillán E, Bautista M, Gayosso-de-Lucio JA, Reyes-Rosales Y, Posadas-Mondragon A, Morales-González A, Soriano-Ursúa MA, García-Machorro J, Madrigal-Bujaidar E, Álvarez-González I, Morales-González JA. World J Gastroenterol 2015; 21(25)7718-7729.
2016
29. Anticonvulsant and toxicological evaluation of para-fluorinated/chlorinated derivatives of 3-hidroxy, 3-ethyl, 3-phenylpropionamide. Osvaldo Garrido-Acosta, Sergio E Meza-Toledo, Liliana Anguiano-Robledo, Marvin A Soriano-Ursúa, Jose Correa Basurto, Asghar Davood, and Germán Chamorro Cevallos. BioMed Res Int. 2016. ID 3978010 http://dx.doi.org/10.1155/2016/397801
30. Current data regarding the structure-toxicity relationship ofboron-containing compounds. Farfán-García ED, Castillo-Mendieta NT, Ciprés-Flores FJ, Padilla-Martínez II, Trujillo-Ferrara JG and Soriano-Ursúa MA. Toxicology Letters. 2016. 258:115-125.
31. Disruption of motor behavior and injury tothe CNS induced by 3-thienylboronic acid in mice. Toxicology and Applied Pharmacology. 2016. 307:130-137 doi:10.1016/j.taap.2016.08.002

2017
32. Boron's journey: Advances in the study and applicationof pharmacokinetics. Expert Opinion on Therapeutic Patents. 2017. 27(2):203-215.
33. Design, in silico studies, synthesis and in vitro evaluation of oseltamivir derivatives as inhibitors of neuraminidase from influenza A virus H1N1. Eur J Med Chem. 2017 Mar 10;128:154-167.
34.Effects of hydrogen peroxide on phenylephrine-induced contraction of abdominal or thoracic aorta from adult rats.  Int J Clin Exp Pathol 2017;10(5):5105-5116.
35. Scope of translational medicine in developing boron-containing compounds for therapeutics. World Journal of Traslational Medicine. 2017; 6(1):1-9.
36. Scope of Lipid Nanoparticles in Neuroscience: Impact on the Treatment of Neurodegenerative Diseases. Current Pharmaceutical Design. 2017.2017;23(21):3120-3133.
37. Not all boronic acids with a five-membered cycle induce tremor, neuronal damage and decreased dopamine. Neurotoxicology. 2017, 62:92-99.

2018
38. Advances of bioinformatics applied to development and evaluation of boron-containing compounds. Current Organic Chemistry. 2018; 22(3):298-306.
39. Effect of tibolone on kinases and phosphatases that regulate the expression and phosphorylation of Tau in rats exposed to ozone. Neural Regeneration Research, 2018. 13(3):440-448.
40. Crystal structure, DFT calculations and evaluation as AChE inhibitor of 2-(2-(3,4-dimethoxyphenyl)ethyl)isoindoline-1,3-dione. Chemistry Central Journal. 2018. 12(1):74. doi: 10.1186/s13065-018-0442-1.
41. Several effects of boron are induced by uncoupling steroid hormones from their transporters in blood. Medical Hypotheses. 2018. 118:78-83. doi: 10.1016/j.mehy.2018.06.024.
42. Isoindolines/isoindoline-1,3-diones as AChE inhibitors against Alzheimer's disease, evaluated by an improved ultra-micro assay. Medicinal Chemistry Research. 2018. 27(9): 2187-2198. https://doi.org/10.1007/s00044-018-2226-5.
43. More than boric acid: Increasing relevance of boron in medicine. World J Translational Med. 2018.7(1):1-4.
44.Profile of three boron-containing compounds on the body weight, metabolism and inflammatory markers of diabetic rats. J. Trace Elem. Med. Biol. 2018. 50:424-429. Doi: 10.1016/j.jtemb.2018.08.009
45. Differences in brain regions of three mice strains identified by label-free Micro-Raman. Spectroscopy Letters. 2018, 51(7):356-366. doi.org/10.1080/00387010.2018.1473883.

2019
46. Pharmacokinetics and tissue distribution of N-(2-hydroxyphenyl)-2-propylpentanamide in Wistar Rats and its binding properties to human serum albumin. J Pharm Biomed. Anal. 2019. 162:130-139.  doi.org/10.1016/j.jpba.2018.09.010
47. Cell-based assays and Molecular Dynamics analysis of a boron-containing agonist with different profiles of binding to human and guinea pig beta2 adrenoceptors" Eur. Biophysics J. 2019. 48(1):83-97. Doi: 10.1007/s00249-018-1336-9
48. Synthesis and biological evaluation of novel 2,3-disubstituted benzofuran analogues of GABA as neurotropic agents. Medicinal chemistry. 2019. 15(1):77-86. DOI:10.2174/1573406414666180524091745
49. Theoretical coupling and stability of boronic acid adducts with catecholamines. Letters in Drug Design & Discovery. 2019. 16(4): 467-475. DOI:10.2174/1570180815666180710101604
50. Design, synthesis and in vitro evaluation of a Dopa-organoboron compound that acts as a bladder relaxant through non-catecholamine receptors. Molecular Diversity. 2018. DOI:10.1007/s11030-018-9883-7.

51. Turning fear of boron toxicity into boron-containing drug design. Current Medicinal Chemistry. 2019. 26(26):5003-5004. DOI:10.2174/0929867326666190327154954
52. Editorial: Chemico-Biological Activity and Medicinal Chemistry of Boron-Containing Compounds. (FREE ACCESS)
53. Beta-Blockers And Salbutamol Limited Emotional Memory Disturbance And Damage Induced By Orchiectomy In The Rat Hippocampus. Life Sciences. 2019, 224:128-137. DOI:2019. 10.1016/j.lfs.2019.03.043.
54. Monoamines and their derivatives on GPCRs: potential therapy for Alzheimer’s Disease. Current Alz Res. 2019. DOI: 10.2174/1570159X17666190409144558
55. Effects of boron-containing compounds on immune responses: review and patenting trends. Exp Opin Ther Pat. 2019, 29(5):339-351. DOI: 10.1080/13533776.2019.1612368

2020
56. Molecular insights into how SHBG dimerization exerts changes on ligand molecular recognition. Journal of Steroid Biochemistry and Molecular Biology. 197 (2020) 105502. doi: 10.1016/j.jsbmb.2019.105502.
57. 2-AMINOETHYLDIPHENYL BORINATE: a multitarget compound with potential as a drug precursor. Current Molecular Pharmacology. 2020, 13(1):57-75. Doi:10.2174/1874467212666191025145429.
58. Identification of two arylimides as cholinesterase inhibitors and testing of propranolol addition on impaired rat memory. Drug Development Research. 2020. 81(2):256-266. DOI: 10.1002/ddr.21633
59. Inhibitory activity on cholinesterases produced by aryl-phthalimide derivatives: Green synthesis, in silico and in vitro evaluation. Medicinal Chemistry Research. 2020. 29(6):1030-1040. https://doi.org/10.1007/s00044-020-02543-2.
60. Olive oil limited motor disruption and neuronal damage in parkinsonism induced by MPTP administration" Toxicology Research and Applications. 2020. 4:1-9. https://doi.org/10.1177/2397847320922939 Free access.
61. Flavolignans from sylimarin as Nrf2 Bioactivators and their therapeutic Applications. Biomedicines. 2020. 8(5):122. Free access.

62. Docking simulations exhibit bortezomib and other boron-containing peptidomimetics as potential inhibitors of SARS-CoV-2 main protease. Current Chemical Biology. 14:xx. Open access.

2021

63. 1-Boc-piperidine-4-carboxaldehyde prevents binge eating behaviour and anxiety in rats. Pharmacology. 2021; 106, 305-315.https://doi.org/10.1159/000513376

64. Effects of boron-containing compounds in the fungal kingdom. J Trace Elem Med Biol. 2021; 65: 126714 https://doi.org/10.1016/j.jtemb.2021.126714

65. Candida glabrata antifungal resistance and virulence factors, a perfect pathogenic. Pharmaceutics, 2021, 13(10), 1529.

2022

66. Interactions of a boron-containing levodopa derivative on D2 dopamine receptor and its effects in a Parkinson disease model. Journal of Biological Inorganic chemistry, 2022 Feb;27(1):121-131. doi:10-1007/s00775-021-01915-2. https://rdcu.be/cBLBL

67. In silico and in vivo neuropharmacological evaluation of two γ-amino acid isomers derived from 2,3-disubstituted benzofurans as ligands of GluN1-GluN2A NMDA receptor. Amino Acids (Springer-nature) 2022; 54:215-228. doi: 10.1007/s00726-021-03108-2.

68.Diversity of effects induced by boron-containing compounds on immune response cells and on antibodies in basal state. Journal of Trace Elements in Medicine and Biology. 2022. 69:126901. doi:10.1016/j.jtemb.2021.126901.

69. Polyphenols as potential enhancers of stem cell therapy against neurodegeneration. Neural Regeneration Research, 2022; 17(10) 2093-2101. DOI: 10.4103/1673-5374.335826

70. Does the Fetus Limit Antibiotic Treatment in Pregnant Patients with COVID-19? Antibiotics 2022, 11(2), 252.

71. Synthesis, In Silico, and Biological Evaluation of a Borinic Tryptophan-Derivative That Induces Melatonin-like Amelioration of Cognitive Deficit in Male Rat. Int. J. Mol. SCI. 10.3390/ijms23063229.

72. Identification and evaluation of boronic compounds ameliorating cognitive deficit in orchiectomized rats. J. Trace Elem Med. Biol. 2022, https://doi.org/10.1016/j.jtemb.2022.126979.

73. Global longitudinal strain is superior to ejection fraction for detecting myocardial dysfunction in end-stage renal disease with hyperparathyroidism. World Journal of Cardiology. 2022.

74. Tibolone improves memory and decreases the content of beta-amyloid peptides and Tau protein in the hippocampus of a mice model of Alzheimer’s disease. Journal of Alzheimer’s Disease. 2022. 90(4) 1437-1447.

2023:

75. Boron-containing compounds for prevention, diagnosis, and treatment of human metabolic disorders. Biol Trace Elem Res, 2023. 201:2222-2239.

76. Boron-containing compounds on neurons: actions and potential applications for treating neurodegenerative diseases. Journal of inorganic biochemistry. 238 (2023) 112027.

77. Effects of Boron-Containing Compounds on Liposoluble Hormone Functions. Inorganics 2023, 11(2), 84; https://doi.org/10.3390/inorganics11020084

78. Synthesis, in-silico, in-vivo, and ex-vivo evaluation of a boron-2 containing quinolinate derivative with presumptive action on 3 mGluR. Inorganics 2023. https://www.mdpi.com/2304-6740/11/3/94

79. Reverse Screening of Boronic Acid Derivatives: Analysis of Potential Antiproliferative Effects on a Triple-Negative Breast Cancer Model In Vitro. Inorganics 2023, 11(4), 165.

80. A Boron-Containing Analogue of Acetaminophen Induces Analgesic Effect in Hot Plate Test and Limited Hepatotoxicity. Inorganics 2023, 11(6), 261.

81. Boron Applications in Prevention, Diagnosis and Therapy for High Global Burden Diseases. Inorganics 2023, 11(9), 358.

82. The cracked potential of boron-containing compounds in Alzheimer’s Disease. Central Nervous System Agents in Medicinal Chemistry. 2023. 23, 213-221.

83. In silico identification of a biarylamine acting as agonist at human β3 adrenoceptors and exerting BRL37344-like effects on mouse metabolism. Naunyn-Schmiedeberg's Archives of Pharmacology. 2023. https://doi.org/10.1007/s00210-023-02753-6.

2024:

84. In vitro and in vivo evaluation of nanoliposomes loading quercetin and 3-bromopyruvate against glioma. Future Journal of Pharmaceutical Sciences.2024, 10, 7. https://doi.org/10.1186/s43094-023-00575-0.

85. The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry and Emerging Pharmacology. Chemical Reviews. 2024. https://doi.org/10.1021/acs.chemrev.3c00663

86. Effectiveness of omega-3 fatty acid supplementation for improving the metabolic and inflammatory profiles of Mexican adults hospitalized with COVID-19. MDPI Diseases. 2024, 12(1): 28.

87. Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats. Fundamental & Clinical Pharmacology, 2024, Accepted.

Chapters:

1. "Tratamiento farmacológico en la enfermedad de Parkinson"(2021) en "Nuevos fármacos y terapias en medicina" Editado por la Dra. Josefina Altamira García, Universidad Autónoma de Tamaulipas. Impresiones de UAT.
2. "Diversity of mechanisms for Boron toxicity in mammals" (2020) in "Metal and metalloids toxicity" edited by Dr. Debasis Bagchi, Department of Pharmacological and Pharmaceutical Sciences, Houston University, USA. For Taylor & Francis Group.

3. The Cytoprotective Activity of Nrf2 is Regulated by Phytochemicals (Sulfuraphane, Curcumin, and Silymarin) (2022) in Reference Series in Phytochemistry. Plant Antioxidants and Health. Springer-Nature.

4. Antimicrobial (Viral, Bacterial, Fungal and Parasitic) mechanisms of action of Boron-containing compounds (2022). Viral, Parasitic, Bacterial, and Fungal Infections being edited by Drs. Bagchi, Das, and Downs. Elsevier.

Reviewer for: JACS, JMedChem, Bioorg Med Chem, MDPI, CurrPharmDesign, CurrMedChem, World J Gastroenterol, MedChemRes, Molecular Diversity, Molecular Biology Reports, Neural Reg Res, LivestockSci, JMolModel, JAfricanPharm, JProteomBioinf, Liberties, JMexChemSoc.

Preprint: https://chemrxiv.org/articles/Theoretical_Evaluation_of_Bortezomib_and_Other_Boron-Containing_Compounds_as_Inhibitors_of_SARS-CoV-2_Main_Protease/12047346/1

Editorial board member:
-World Journal of Translational Medicine
- Letters in Drug Design & Discovery
- Current Chemical Biology
- Current Medicinal Chemistry (as Guest Editor of a special issue)

- World Journal of Translational medicine

- World Journal of Stem Cells

- Inorganics MDPI

- Heliyon

Member of American Chemical Society
Member of Sistema Nacional de Investigadores de México

Dr. Soriano-Ursúa is recipient of the prestigious “Boron in the Americas Award” (for Exceptional Service to Boron Research and Commitment to Excellence) in 2022 for contribution to Boron based medicinal chemistry.

Researching ESM_IPN: Boron on GPCR

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